There is a component called urea, which is the result of the metabolism of the proteins that are made in the liver in human blood. During digestion, proteins are separated into amino acids containing nitrogen, which is released as ammonium ion to form urea that is eliminated in the urine. If the kidney doesn't work well, urea accumulates in the blood and its concentration resulting in high urea in the blood rises.
* Only one "like" per meaning and day, the more "likes" the meaning will appear higher in the list