It means that he is originally from Guaira or La Guaira. Resident in Guaira or La Guaira. Related to La Guaira or Guaira. Guaira is the name of a Paraguayan people and there was a Province called Guayra. La Guaira is the name of a Venezuelan port, close to Caracas and also from a state (formerly State of Vargas). There is also a municipality of Brazil, with that name and belonging to the State of Paraná. The word in Tupi-Guarani means "Place of difficult access".