Locution to mention how small the world is, and that one can find acquaintances that it supposes in distant places also within its environment. The least forced origin seems to be in the Renaissance world maps that were drawn on a relatively small canvas or cloth (a handkerchief), with which an analogy was made.
It is an expression used in Colombia and that refers to everything being small or simple when compared to the universe. It's similar to "how small the world is." It means that everything can be known or known, that there is nothing that can remain hidden forever. That anywhere we can find someone who knows us or who knows us.