1. Any change in the sequence of genomic DNA. 60; 62; 2-br is called phonetic change to any changes in the level of phonetic and phonological language, alter the articulation of a particular phoneme. 60; br 62; 3.-the definition given by De Vries ( 41 1901; the mutation was any heritable change in hereditary material which cannot be explained by recombination or segregation.The definition of mutation from the knowledge that the hereditary material is DNA and the double helix proposal to explain the structure of the hereditary material (Watson and Crick, 1953; 41, would be that a mutation is any change in the sequence of nucleotides in the DNA.The mutation is the source of genetic variability in populations, while recombination to create new combinations from those generated by mutation, is the secondary source of genetic variability.
