It was the name of a very common painkiller in Colombia. Comparatively, it was as popular as Acetaminophen is today. His great competitors were the Best and the Conmel (for toothache). By extension, it is said in Colombia Calmadoral to all that soothes a pain, an affliction or a penalty; that's why in a colloquial way we say to the brandy or the liquor in general.