It is said of the climactic moment, the highest in tension or gravity, used both in medicine for the most serious point of a disease, and in the arts for the most tense moment in a dramatic work. Although it comes to us from French, the origin is Greek, where 945; 954; 956; 951; ( akmé ) is "tip, end, heyday". It can be used as male or female. See doctor/acmé .