A toxoid ( in international medical literature is also known as anatoxina1 ) It is a bacterial toxin whose toxicity has been attenuated or abolished by a chemical ( 41 formaldehyde; or by effects of the heat, while is extraditing other properties, such as its immunogenicity. Thus, when used during vaccination generates an immune response forming an immunological memory against the molecular markers of tetanus, without producing a Toxin-induced disease.Toxoids are used in vaccines against tetanus, 2 botulism or difteria.3